Dr. Xin-Yuan Liu received his Bachelor degree from the department of chemistry, Anhui Normal University in 2001 and a Master degree in 2004 from Anhui Normal University in Cooperation with Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, China. Then, he became a Ph.D. candidate in Department of Chemistry, the University of Hong Kong under the supervision of Prof. Chi-Ming Che, and has been awarded a Ph.D. degree in 2010. He then successfully applied a Post-doctoral Fellow position in the University of Hong Kong and continued to work in the laboratory of Prof. Che. In 2011, he joined in the group of Prof. Carlos F. Barbas III at the Scripps Research Institute for a postdoc position. In September of 2012, Dr. Liu joined in the Department of Chemistry, SUSTech, and has set up an independent organic chemistry’s research group.His research interests are focused on transition-metal and organocatalyst-catalyzed organic chemistry, homogeneous and heterogeneous catalysis, organofluorine chemistry, and the application of chemistry in biological and medicinal chemistry. He has published more than forty research papers in international journals, including Angewandte Chemie International Edition, Chemical Communications, Organic Letters, Chemistry – A European Journal, ACS Catalysis. Citation times for his research papers have been up to 1300. Dr. Liu has been awarded Award for Outstanding Research Postgraduate Student for 2009-2010 in The University of Hong Kong (2011), and so on.

Research interests：

◆ Catalytic functionalization of unactivated alkenes and alkynes
◆ Asymmetric radical chemistry
◆ Design and application of homogenous and heterogeneous catalysis
◆ Organofluorine chemistry.

Educational background

◆ Ph.D., in Organic Chemistry, The University of Hong Kong, 2010;
◆ M.S., in Organic Chemistry, Anhui Normal University in Cooperation with Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 2004;
◆ B.S., in Chemistry, Anhui Normal University, 2001.

Professional experience

◆ 2012.9, Associate Professor, South University of Science and Technology of China;
◆ 2011-2012, Research Associate, the Scripps Research Institute, USA;
◆ 2010-2011, Post-doctoral Fellow, The University of Hong Kong;
◆ 2004-2005, Research Assistant, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.

Honors & Awards

◆ 2011，Award for Outstanding Research Postgraduate Student for 2009-2010 in The University of Hong Kong
◆ 2013，Peacock Plan Awardee, Shenzhen

Publications

93. Fu-Li Wang+, Chang-Jiang Yang+, Ji-Ren Liu+, Ning-Yuan Yang, Xiao-Yang Dong , Ruo-Qi Jiang, Xiao-Yong Chang , Zhong-Liang Li, Guo-Xiong Xu, Dai-Lei Yuan, Yu-Shuai Zhang, Qiang-Shuai Gu,* Xin Hong,* and Xin-Yuan Liu* "Mechanism-based ligand design for copper-catalysed enantioconvergent C(sp3)–C(sp) cross-coupling of tertiary electrophiles with alkynes" Nat. Chem. 2022, 14, 949.

92. Xian-Yan Cheng+, Yu-Feng Zhang+*, Jia-Huan Wang, Qiang-Shuai Gu, Zhong-Liang Li*, and Xin-Yuan Liu* "A Counterion/Ligand-Tuned Chemo- and Enantioselective Copper-Catalyzed Intermolecular Radical 1,2-Carboamination of Alkenes." J. Am. Chem. Soc. 2022, 144, 18081.

91. Xiao-Yang Dong, Zhong-Liang Li, Qiang-Shuai Gu, and Xin-Yuan Liu* "Ligand Development for Copper-Catalyzed Enantioconvergent Radical Cross-Coupling of Racemic Alkyl Halides." J. Am. Chem. Soc. 2022, 144, 17319.

90. Peng-Fei Wang+, Jiao Yu+, Kai-Xin Guo+, Sheng-Peng Jiang, Ji-Jun Chen, Qiang-Shuai Gu, Ji-Ren Liu, Xin Hong, Zhong-Liang Li,* and Xin-Yuan Liu* "Design of Hemilabile N,N,N-Ligands in Copper-Catalyzed Enantioconvergent Radical Cross-Coupling of Benzyl/Propargyl Halides with Alkenylboronate Esters." J. Am. Chem. Soc. 2022, 144, 6442.

89. Fu-Li Wang+, Lin Liu+, Chang-Jiang Yang, Cheng Luan, Yang Jing, Ji-Jun Chen, Qiang-Shuai Gu, Zhong-Liang Li*, and Xin-Yuan Liu* "Synthesis of α-Quaternary β-Lactams via Copper-Catalyzed Enantioconvergent Radical C(sp3)–C(sp2) Cross-Coupling with Organoboronate Esters." Angew. Chem. Int. Ed. 2022, 61, e202214709.

88. Wu Yang+, Lin Liu+, Jiandong Guo+, Shou-Guo Wang, Jia-Yong Zhang, Li-Wen Fan, Yu Tian, Li-Lei Wang, Cheng Luan, Zhong-Liang Li, Chuan He, Xiaotai Wang*, Qiang-Shuai Gu*, Xin-Yuan Liu* "Enantioselective Hydroxylation of Dihydrosilanes to Si-Chiral Silanols Catalyzed by In Situ Generated Copper(II) Species." Angew. Chem. Int. Ed. 2022, 61, e202205743.

87. Feng-Ling Qing,* Xin-Yuan Liu,* Jun-An Ma,* Qilong Shen,* Qiuling Song,* Pingping Tang* "A Fruitful Decadeof Organofluorine Chemistry: New Reagents and Reactions." CCS Chem. 2022, 4, 2518.

86. Cheng Luan+, Chang-Jiang Yang+, Lin Liu, Qiang-Shuai Gu*, and Xin-Yuan Liu* "Transition metal-catalyzed enantioselective C–P coupling reactions for the construction of P-stereogenic centers." Chem Catal. 2022, 2, 2876.

85. Na Wang, Li-Wen Fan, Jin Zhang, Qiang-Shuai Gu, Jin-Shun Lin, Guo-Qiang Chen,* Xin-Yuan Liu,* and Peiyuan Yu* "Chiral N-triflylphosphoramide-catalyzed asymmetric hydroamination of unactivated alkenes: a hetero-ene reaction mechanism." Org. Chem. Front. 2022, 9, 1649.

84. Jun-Bin Tang, Jun-Qian Bian, Yu-Shuai Zhang, Yong-Feng Cheng, Han-Tao Wen, Zhang-Long Yu, Zhong-Liang Li, Qiang-Shuai Gu,* Guo-Qiang Chen,* and Xin-Yuan Liu* "Copper-Catalyzed anti-Selective Radical 1,2-Alkylarylation of Terminal Alkynes." Org. Lett. 2022, 24, 2536.

83. Lin Liu, Kai-Xin Guo, Yu Tian, Chang-Jiang Yang, Qiang-Shuai Gu, Zhong-Liang Li, Liu Ye*, and Xin–Yuan Liu* "Copper-Catalyzed Intermolecular Enantioselective Radical Oxidative C(sp3)-H/C(sp)-H Cross-Coupling with Rationally Designed Oxazoline-Derived N,N,P(O)-Ligand." Angew. Chem. Int. Ed. 2021, 60, 26710

82. Yu-Feng Zhang+, Xiao-Yang Dong+, Jiang-Tao Cheng+, Ning-Yuan Yang, Li-Lei Wang, Fu-Li Wang, Cheng Luan, Juan Liu, Zhong-Liang Li, Qiang-Shuai Gu, and Xin-Yuan Liu* "Enantioconvergent Cu-Catalyzed Radical C−N Coupling of Racemic Secondary Alkyl Halides to Access αChiral Primary Amines" J. Am. Chem. Soc. 2021, 143, 15413.

81. Chi Zhang, Zhong-Liang Li, Qiang-Shuai Gu* & Xin-Yuan Liu* "Catalytic enantioselective C(sp3)–H functionalization involving radical intermediates." Nat. Commun. 2021, 12, 475.

80. Huan Zhou+, Zhong-Liang Li+, Qiang-Shuai Gu, and Xin-Yuan Liu* "Ligand-Enabled Copper(I)-Catalyzed Asymmetric Radical C(sp3)−C Cross-Coupling Reactions." ACS Catal. 2021, 11, 7978.

79. Jiao Yu, Ning-Yuan Yang, Jiang-Tao Cheng, Tian-Ya Zhan, Cheng Luan, Liu Ye, Qiang-Shuai Gu, Zhong-Liang Li,* Guo-Qiang Chen,* and Xin-Yuan Liu* "Copper-Catalyzed Radical 1,2-Carbotrifluoromethylselenolation of Alkenes under Ambient Conditions" Org. Lett. 2021, 23, 1945.

78. Zheng-Hua Zhang,  He Wei,  Zhong-Liang Li*,  Xin-Yuan Liu* "Recent Advances in Radical-Involved Alkynylation of Unactivated C(sp3)–H Bonds by Hydrogen Atom Abstraction." Synlett 2021, 32, 362.

77. Xiao-Long Su+, Sheng-Peng Jiang+, Liu Ye , Guo-Xing Xu, Ji-Jun Chen, Qiang-Shuai Gu, Zhong-Liang Li* , Xin-Yuan Liu* "A general copper-catalyzed radical C(sp3)-C(sp2) cross-coupling to access 1,1-diarylalkanes under ambient conditions." Tetrahedron 2021, 89, 132152.

76. Zhuang Li+,  Xian-Yan Cheng+,  Ning-Yuan Yang, Ji-Jun Chen, Wen-Yue Tang, Jun-Qian Bian, Yong-Feng Cheng, Zhong-Liang Li, Qiang-Shuai Gu,* and Xin-Yuan Liu* "A Cobalt-Catalyzed Enantioconvergent Radical Negishi C(sp3)−C(sp2) Cross-Coupling with Chiral Multidentate N,N,PLigand." Organometallics 2021, 40, 2215.

75. Ning-Yuan Yang,  Zhong-Liang Li,*  Xin-Yuan Liu* "Recent progress in 1,1-diborylalkanes-involved asymmetric synthesis." Journal of Molecular Science, 2021, 37, 1.

74. Huan Zhou, Xin-Yuan Liu* "Photoinduced Copper-Catalyzed Asymmetric C—O Cross-Coupling" Chin. J. Org. Chem. 2021, 41, 4510.

73. Xiao-Yang Dong+, Tian-Ya Zhan+, Sheng-Peng Jiang, Xiao-Dong Liu, Liu Ye, Zhong-Liang Li, Qiang- Shuai Gu, and Xin-Yuan Liu* "Copper-Catalyzed Asymmetric Coupling of Allenyl Radicals with Terminal Alkynes to Access Tetrasubstituted Allenes."  Angew. Chem. Int. Ed. 2021, 60, 2160.

72.  Xiao-Long Su+, Liu Ye+, Ji-Jun Chen+, Xiao-Dong Liu+, Sheng-Peng Jiang, Fu-Li Wang, Lin Liu, Chang-Jiang Yang, Xiao-Yong Chang, Zhong-Liang Li, Qiang-Shuai Gu, and Xin-Yuan Liu* "Copper-Catalyzed Enantioconvergent Cross-Coupling of Racemic Alkyl Bromides with Azole C(sp3)–H Bonds."  Angew. Chem. Int. Ed. 2021, 60, 380.

71. Sheng-Peng Jiang, Xiao-Yang Dong, Qiang-Shuai Gu, Liu Ye, Zhong-Liang Li,* and Xin-Yuan Liu* "Copper-Catalyzed Enantioconvergent Radical Suzuki–Miyaura C(sp3)–C(sp2) Cross-Coupling." J. Am. Chem. Soc. 2020, 142, 19652.

70. Zhe Wang,+ Jiang-Tao Cheng,+ Zhichao Shi, Na Wang, Feng Zhan, Sheng-Peng Jiang, Jin-Shun Lin,* Yuyang Jiang,* Xin-Yuan Liu*  "Catalytic Asymmetric Intermolecular Radical Aminotrifluoromethylation of Alkenes with Hydrazines by Cu(I)/CPA Cooperative Catalysis." ChemCatChem 2020, 13, 185.

69. Hai-Dong Xia,+ Zhong-Liang Li,+ Qiang-Shuai Gu,+ Xiao-Yang Dong,+ Jia-Heng Fang, Xuan-Yi Du, Li-Lei Wang, and Xin-Yuan Liu* "Photoinduced Copper-Catalyzed Asymmetric Decarboxylative Alkynylation with Terminal Alkynes." Angew. Chem. Int. Ed. 2020, 59, 16926. 

68.  Chang-Jiang Yang+, Chi Zhang+, Qiang-Shuai Gu+ , Jia-Heng Fang, Xiao-Long Su, Liu Ye, Yan Sun, Yu Tian, Zhong-Liang Li and Xin-Yuan Liu* "Cu-catalysed intramolecular radical enantioconvergent tertiary β-C(sp3)–H amination of racemic ketones." Nat. Catal. 2020, 3, 539 .

67. Yong-Feng Cheng+, Ji-Ren Liu+, Qiang-Shuai Gu+, Zhang-Long Yu+, Jian Wang, Zhong-Liang Li, Jun-Qian Bian, Han-Tao Wen, Xiao-Jing Wang, Xin Hong* & Xin-Yuan Liu* "Catalytic enantioselective desymmetrizing functionalization of alkyl radicals via Cu(I)/CPA cooperative catalysis. " Nat. Catal. 2020, 3, 401.  

66. Xiao-Yang Dong+, Jiang-Tao Cheng+, Yu-Feng Zhang+, Zhong-Liang Li+, Tian-Ya Zhan, Ji-Jun Chen, FuLi Wang,  Ning-Yuan Yang, Liu Ye, Qiang-Shuai Gu, and Xin-Yuan Liu* ''Copper-Catalyzed Asymmetric Radical 1,2-Carboalkynylation of Alkenes with Alkyl Halides and Terminal Alkynes.'' J. Am. Chem. Soc. 2020, 142, 9501. 

65. Xi-Tao Li+, Ling Lv+, Ting Wang+, Qiang-Shuai Gu, Guo-Xing Xu, Zhong-Liang Li, Liu Ye, Xinhao Zhang, Gui-Juan Cheng,* and Xin-Yuan Liu* ''Diastereo- and Enantioselective Catalytic Radical Oxysulfonylation of Alkenes in β,γ-Unsaturated Ketoximes.'' Chem 2020, 6, 1692.

64. Zhong-Liang Li,† Gui-Chun Fang,† Qiang-Shuai Gu † and Xin-Yuan Liu * ''Recent advances in copper-catalysed radical-involved asymmetric 1,2-difunctionalization of alkenes'' Chem. Soc. Rev. 2020, 49, 32.

63. Zhang-Long Yu+, Yong-Feng Cheng+, Na-Chuan Jiang, Jian Wang, Li-Wen Fan, Yue Yuan, Zhong-Liang Li, Qiang-Shuai Gu* and Xin-Yuan Liu* ''Desymmetrization of unactivated bis-alkenes via chiral Brønsted acid-catalysed hydroamination'' Chem. Sci. 2020, 11, 5987.

62. Yu-Xi Cao, Xiao-Yang Dong, Jun Yang, Sheng-Peng Jiang, Shuangliu Zhou, Zhong-Liang Li,* Guo-Qiang Chen,* and Xin-Yuan Liu* ”A Copper‐Catalyzed Sonogashira Coupling Reaction of Diverse Activated Alkyl Halides with Terminal Alkynes Under Ambient Conditions.” Adv. Synth. Catal. 2020, 362, 2280.

61.   Zhen-Hua Zhang+, Xiao-Yang Dong+, Xuan-Yi Du+, Qiang-Shuai Gu , Zhong-Liang Li & Xin-Yuan Liu* ''Copper-catalyzed enantioselective Sonogashira-type oxidative cross-coupling of unactivated C(sp3)−H bonds with alkyne.'' Nat. Commun. 2019,  10,  5689.

60. Liu Ye+, Yu Tian+, Xiang Meng, Qiang-Shuai Gu and Xin-Yuan Liu*  ''Cu(I)/Chiral Phosphoric Acid-Catalyzed Radical-Involved Enantioselective Intramolecular Amination of Allylic and Benzylic C–H Bonds.'' Angew. Chem. Int. Ed. 2020, 59, 1129.

59. Xiao-Yang Dong+, Yu-Feng Zhang+, Can-Liang Ma+, Qiang-Shuai Gu+, Fu-Li Wang+, Zhong-Liang Li, Sheng-Peng Jiang and Xin-Yuan Liu* "A general asymmetric copper-catalysed Sonogashira C(sp3)–C(sp) coupling" Nat. Chem. 2019, 11, 1158.

58. Qiang-Shuai Gu, Zhong-Liang Li, and Xin-Yuan Liu* "Copper(I)-Catalyzed Asymmetric Reactions Involving Radicals." Acc. Chem. Res. 2020, 53, 170.

57. Jin-Shun Lin, Tao-Tao Li, Ji-Ren Liu, Guan-Yuan Jiao, Qiang-Shuai Gu, Jiang-Tao Cheng, Yu-Long Guo, Xin Hong*, and Xin-Yuan Liu* "Cu/Chiral Phosphoric Acid-Catalyzed Asymmetric Three-Component Radical-Initiated 1,2-Dicarbofunctionalization of Alkenes." J. Am. Chem. Soc. 2019, 141, 1074.

56. Jin-Shun Lin, Tao-Tao Li, Guan-Yuan Jiao, Qiang-Shuai Gu, Jiang-Tao Cheng, Ling Lv, and Xin-Yuan Liu*, "Chiral Brønsted Acid‐Catalyzed Dynamic Kinetic Asymmetric Hydroamination of Racemic Allenes and Asymmetric Hydroamination of Dienes." Angew. Chem. Int. Ed. 2019, 58, 7092.

55. Yang Zeng, Xiao-Dong Liu, Xian-Qi Guo, Qiang-Shuai Gu*, Zhong-Liang Li*, Xiao-Yong Chang & Xin-Yuan Liu* "Cu/Chiral Phosphoric Acid-Catalyzed Radical-Initiated Asymmetric Aminosilylation of Alkene with Hydrosilane" Sci. China Chem. 2019, 62, 1529.

54. GuiChun Fang, YongFeng Cheng, ZhangLong Yu, ZhongLiang Li, XinYuan Liu，"Recent Advances in FirstRow Transition Metal/Chiral Phosphoric Acid Combined Catalysis." Top. Curr. Chem. 2019, 377, 23.

53. Na Wang, Qiang-Shuai Gu, Zhong-Liang Li, Zhuang Li, Yu-Long Guo, Zhen Guo, and Xin-Yuan Liu*, "Direct Photocatalytic Synthesis of Medium-Sized Lactams through C–C Bond Cleavage." Angew. Chem. Int. Ed. 2018, 57, 14225.

52. Xi-Tao Li, Qiang-Shuai Gu, Xiao-Yang Dong, Xiang Meng, and Xin-Yuan Liu*, "Cinchona Alkaloid‐Based Sulfonamide/Copper Catalyst for Asymmetric Radical Oxytrifluoromethylation of Alkenyl Oximes." Angew. Chem. Int. Ed. 2018, 57, 7668.

51. Liu Ye, Qiang-Shuai Gu, Guo-Cong Chen, and Xin-Yuan Liu,* "Construction of Bicyclo[3.1.0]hexanes Containing Vicinal All-Carbon Quaternary Stereocenters via Radical Asymmetric Intramolecular α-Cyclopropanation of Aldehydes." Nat. Commun. 2018, 9, 227.

50. Jin-Hao Zhao, Yong Yang, Jin-Xin Che, Jun Zuo, Xiao-Hua Li, Yong-Zhou Hu, Xiao-Wu Dong,* Liang Gao,* and Xin-Yuan Liu*, “Compartmentalization of Incompatible Polymers within Metal–Organic Frameworks towards Homogenization of Heterogeneous Hybrid Catalysts for Tandem Reactions.” Chem. Eur. J. 2018, 24, 9903.

49. Na Wang, Jian Wang, Yu-Long Guo, Lei Li, Yan Sun, Zhuang Li, Hong-Xia Zhang, Zhen Guo, Zhong-Liang Li* and Xin-Yuan Liu *, “Oximinotrifluoromethylation of unactivated alkenes under ambient conditions.” Chem. Commun. 2018, 54, 8885.

48. Na Wang, Liu Ye, Zhong-Liang Li, Lei Li, Zhuang Li, Hong-Xia Zhang, Zhen Guo, QiangShuai Gu* and Xin-Yuan Liu*, “Hydrofunctionalization of Alkenols Triggered by Addition of Diverse Radicals to Unactivated Alkenes and Subsequent Remote Hydrogen Atom Translocation.” Org. Chem. Front. 2018, 5, 2810.

47. Xiao-Wu Dong*, Yong Yang, Jin-Xin Che, Jun Zuo, Xiao-Hua Li, Liang Gao, Yong-Zhou Hu and Xin-Yuan Liu*, “Heterogenization of homogeneous chiral polymers in metal–organic frameworks with enhanced catalytic performance for asymmetric catalysis.” Green Chem. 2018, 20, 4085.

46. Xi-Tao Li, Ling Lv, Qiang-Shuai Gu,*, and Xin-Yuan Liu*, “Copper-catalyzed radical oxytrifluoromethylation of alkenyl oximes at ambient temperature.” Tetrahedron, 2018, 74, 6041.

45. Yu Tian, Su Chen, Qiang-Shuai Gu, Jin-Shun Lin, Xin-Yuan Liu*, “Amino- and azidotrifluoromehtylation of alkenes.” Tetrahedron Lett. 2018, 59, 203. (Invited Digest)

44. Na Wang, Qiang-Shuai Gu*, Yong-Feng Cheng, Lei Li, Zhong-Liang Li, Zhen Guo*, and Xin-Yuan Liu*, “Visible-Light Promoted Preparation of Trifluoromethylated Tetrahydrofuran and Tetrahydropyran.” Chin. J. Org. Chem. 2019, 39, 200.

43. Xue-Fei Li, Jin-Shun Lin, Jian Wang, Zhong-Liang Li, Qiang-Shuai Gu, and Xin-Yuan Liu*, “Cu/Chiral Phosphoric Acid-Catalyzed Asymmetric Radical- Initiated Aminoarylation of Alkenes.” Acta Chim. Sinica 2018, 76, 878.

42. Fu-Li Wang, Xiao-Yang Dong, Jin-Shun Lin, Yang Zeng, Guan-Yuan Jiao, Qiang-Shuai Gu, Xian-Qi Guo, and Xin-Yuan Liu*, “Catalytic Asymmetric Diamination of Unactivated Alkene with Dialkylaminyl Radical” Chem 2017, 3, 979.

41. Lei Li, Zhong-Liang Li, Qiang-Shuai Gu, Na Wang, Xin-Yuan Liu,* "A Remote Radical Vinyl Migration Strategy to Access Medium- and Large-sized Cyclic Alkenes" Sci. Adv. 2017, 3, e1701487.

40. Lei Li, Liu Ye, Shao-Fei Ni, Zhong-Liang Li, Su Chen, Yi-Meng Du, Xiao-Hua Li, Li Dang* and Xin-Yuan Liu,* "Phosphine-catalyzed remote α-C–H bond activation of alcohols or amines triggered by the radical trifluoromethylation of alkenes: reaction development and mechanistic insights" Org. Chem. Front. 2017, 4, 2139.

39. Xue-Fei Li, Jin-Shun Lin and Xin-Yuan Liu,* “Catalytic Radical Intramolecular Aminoperfluoroalkylation and Aminodifluoromethylation of Unactivated Alkenes with Fluoroalkylsulfonyl Chlorides” Synthesis 2017, 49, 4213.
Published as part of the Special Topic Modern Cyclization Strategies in Synthesis

38. Jin-Shun Lin, Fu-Li Wang, Xiao-Yang Dong, Wei-Wei He, Yue Yuan, Su Chen, and Xin-Yuan Liu,* "Catalytic Asymmetric Radical Aminoperfluoroalkylation and Aminodifluoromethylation of Alkenes: A Versatile Platform for Enantioenriched-Fluoroalkyl Amines" Nat. Commun. 2017, 8, 14841.

37. Yong-Feng Cheng, Xiao-Yang Dong, Qiang-Shuai Gu, Zhang-Long Yu, and Xin-Yuan Liu* “Achiral Pyridine Ligand-Enabled Enantioselective Radical Oxytrifluoromethylation of Alkenes with Alcohols” Angew. Chem., Int. Ed. 2017, 56, 8883.

36 Taotao Li, Peng Yu, Yi-Meng Du, Jin-Shun Lin, Yonggang Zhi,* and Xin-Yuan Liu,* "Dual-Catalyzed Enantioselective Remote C−H Functionalization Triggered by Radical Trifluoromethylation of Alkenes: Highly Selective Formation of C−CF3 and C−C Bonds" J. Fluorine Chem. 2017, 203, 210. (invited paper for a special issue).

35 Lei Li, Qiang-Shuai Gu, Na Wang, Ping Song, Zhong-Liang Li, Xiao-Hua Li, Fu-Li Wang, and Xin-Yuan Liu,* "1,2-Difunctionalization-Type (Hetero)arylation of Unactivated Alkenes Triggered by Radical Addition/Remote (Hetero)aryl Migration" Chem. Commun. 2017, 53, 4038.

34. Ping Song, Peng Yu, Jin-Shun Lin, Yiqun Li,* Ning-Yuan Yang, and Xin-Yuan Liu,* "Transition-Metal-Free β C−H Bond Carbonylation of Enamides or Amides with a Trifluoromethyl Group as CO Surrogate for the Synthesis of 1,3-Oxazin-6-ones" Org. Lett. 2017, 19, 1330.

33. Lei Li, Zhong-Liang Li, Fu-Li Wang, Zhen Guo, Yong-Feng Cheng, Na Wang, Chao Fang, Jingjiang Liu, Chunhui Hou, Bin Tan, and Xin-Yuan Liu,* "Radical Aryl Migration Enables Diversity-Oriented Synthesis of Structurally Diverse Medium/Macro- or Bridged-Rings" Nat. Commun. 2016, 7, 13852.

32. Zhong-Liang Li, Xiao-Hua Li, Na Wang, Ning-Yuan Yang, and Xin-Yuan Liu,* "Radical-Mediated 1,2-Formyl/carbonyl-Functionalization of Alkenes and Application to Construction of Medium-Sized-, Fused-, and Bridged-Ring Systems" Angew. Chem., Int. Ed. 2016, 55, 15100.

31. Jin-Shun Lin, Xiao-Yang Dong, Tao-Tao Li, Na-Chuan Jiang, Bin Tan, and Xin-Yuan Liu,* "A Dual-Catalytic Strategy to Direct Asymmetric Radical Aminotrifluoromethylation of Alkenes" J. Am. Chem. Soc. 2016, 138, 9357.

30. Lin Huang, Liu Ye, Xiao-Hua Li, Zhong-Liang Li, Jin-Shun Lin, and Xin-Yuan Liu,* "Stereoselective Radical Cyclization Cascades Triggered by Addition of Diverse Radicals to Alkynes to Construct 6(5)‐6‐5 Fused Rings" Org. Lett., 2016, 18, 5284.

29. Na Wang, Lei Li, Zhong-Liang Li, Ning-Yuan Yang, Zhen Guo,* Hong-Xia Zhang, and Xin-Yuan Liu,* "Catalytic Diverse Radical-Mediated 1,2-Cyanofunctionalization of Unactivated Alkenes via Synergistic Remote Cyano Migration and Protected Strategies" Org. Lett., 2016, 18, 6026.

28. Ning-Yuan Yang, Zhong-Liang Li, Liu Ye, Bin Tan, and Xin-Yuan Liu,* "Organic base-catalysed solvent-tuned chemoselective carbotrifluoromethylation and oxytrifluoromethylation of unactivated alkenes" Chem. Commun., 2016, 52, 9052.
From themed collection 2016 Emerging Investigators by Chem. Commun.

27. Xiao-Long Yu, Liping Kuang, Su Chen, Xiao-Long Zhu, Zhong-Liang Li, Bin Tan, and Xin-Yuan Liu,* "Counteranion-Controlled Unprecedented Diastereo- and Enantioselective Tandem Povarov Reaction for Construction of Bioactive Octahydro-dipyrroloquinolines" ACS Catal. 2016, 6, 6182.

26. Na Wang, Sheng-Cai Zheng, Lin-Lin Zhang, Zhen Guo,* and Xin-Yuan Liu* "Nickel(0)-Catalyzed Denitrogenative Transannulation of Triazoles with Alkynes: Mechanistic Insights of Chemical Reactivity, Regio- and Enantioselectivity from Density Functional Theory and Experiment" ACS Catal. 2016, 6, 3496.

25. Taotao Li, Peng Yu, Jin-Shun Lin, Yonggang Zhi,* and Xin-Yuan Liu,* "Copper-Catalyzed Redox-Triggered Remote C–H Functionalization: Highly Selective Formation of C–CF3 and C–O Bonds" Chin. J. Chem. 2016, 34, 490.
Invited paper for the Special Issue of “Trifluoromethylation and Trifluoromethythiolation Reactions”

24. Can-Liang Ma, Xiao-Hua Li, Xiao-Long Yu, Xiao-Long Zhu, Yong-Zhou Hu, Xiao-Wu Dong,* Bin Tan,* and Xin-Yuan Liu,* "Gold-catalyzed tandem synthesis of bioactive spiro-dipyrroloquinolines and its application in the one-step synthesis of incargranine B aglycone and seneciobipyrrolidine (I)" Org. Chem. Front. 2016, 3, 324.
From themed collection 2015 Emerging Investigators by OCF.

23. Zhi-Jia Fang, Sheng-Cai Zheng, Zhen Guo, Jing-Yao Guo, Bin Tan,* and Xin-Yuan Liu,* "Asymmetric Synthesis of Axially Chiral Isoquinolones: Nickel-Catalyzed Denitrogenative Transannulation" Angew. Chem., Int. Ed. 2015, 54, 9528.

22. Jin-Shun Lin, Peng Yu, Lin Huang, Pan Zhang, Bin Tan,* and Xin-Yuan Liu,* "Brønsted Acid-Catalyzed Asymmetric Hydroamination of Alkenes: Synthesis of Pyrrolidines Bearing a Tetrasubstituted Carbon Stereocenter" Angew. Chem., Int. Ed. 2015, 54, 7847.

21. Peng Yu, Sheng-Cai Zheng, Ning-Yuan Yang, Bin Tan,* and Xin-Yuan Liu,* "Phosphine-Catalyzed Remote β-C-H Functionalization of Amine Triggered by Trifluoromethylation of Alkene: One-Pot Synthesis of Bistrifluoromethylated Enamides and Oxazoles" Angew. Chem., Int. Ed. 2015, 54, 4041.

20. Peng Yu, Jin-Shun Lin, Lei Li, Sheng-Cai Zheng, Ya-Ping Xiong, Li-Jiao Zhao, Bin Tan,* and Xin-Yuan Liu,* "Enantioselective C–H Bond Functionalization Triggered by Radical Trifluoromethylation of Unactivated Alkene" Angew. Chem., Int. Ed. 2014, 53, 11890.

19. Ji-Wei Zhang, Jin-Hui Xu, Dao-Juan Cheng, Chuan Shi, Xin-Yuan Liu,* and Bin Tan,* "Discovery and Enantiocontrol of Axially Chiral Urazoles via Organocatalytic Tyrosine Click Reaction" Nat. Commun. 2016, 7, 10677.

18. Jian Zhang, Shao-Xia Lin, Dao-Juan Cheng, Xin-Yuan Liu,* and Bin Tan,* "Phosphoric Acid-Catalyzed Asymmetric Classic Passerini Reaction" J. Am. Chem. Soc. 2015, 137, 14039.

17. Ye-Hui Chen, Dao-Juan Cheng, Jian Zhang, Yong Wang, Xin-Yuan Liu,* Bin Tan,* "Atroposelective Synthesis of Axially Chiral Biaryldiols via Organocatalytic Arylation of 2 Naphthols" J. Am. Chem. Soc. 2015, 137, 15062.

16. Ming-Yue Wu, Wei-Wei He, Xin-Yuan Liu,* and Bin Tan,* "Asymmetric Construction of Spirooxindoles via Organocatalytic Multicomponent Reactions of Diazooxindoles" Angew. Chem., Int. Ed. 2015, 54, 9409.

15. Dao-Juan Cheng, Liang Yan, Shi-Kai Tian,* Ming-Yue Wu, Lu-Xin Wang, Zi-Li Fan, Sheng-Cai Zheng, Xin-Yuan Liu,* and Bin Tan,* "Highly Enantioselective Kinetic Resolution of Axially Chiral BINAM Derivatives Catalyzed by a Brønsted Acid" Angew. Chem., Int. Ed. 2014, 53, 3684.

14. Lin Huang, Jin-Shun Lin, Bin Tan,* Xin-Yuan Liu,* "Alkene Trifluoromethylation-Initiated Remote α-Azidation of Carbonyl Compounds toward Trifluoromethyl γ-Lactam and Spirobenzofuranone-lactam" ACS Catal. 2015, 5, 2826.

13. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu,* "Metal-Free Direct 1,6- and 1,2-Difunctionalization Triggered by Radical Trifluoromethylation of Alkenes" Org. Lett. 2015, 17, 1589.

12. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu,* "Trifluoromethylation-Initiated Remote Cross-Coupling of Carbonyl Compounds to Form Carbon–Heteroatom/Carbon Bonds" Chem. Eur. J. 2015, 21, 6718.

11. Can-Liang Ma, Xiao-Long Yu, Xiao-Long Zhu, Yong-Zhou Hu, Xiao-Wu Dong, Bin Tan,* and Xin-Yuan Liu,* "Platinum-Catalyzed Tandem Cyclization Reaction to Multiply Substituted Indolines under Microwave-Assisted Conditions" Adv. Synth. Catal. 2015, 357, 569.

10. Lei Li, Jing-Yao Guo, Xing-Guo Liu, Su Chen, Yong Wang, Bin Tan,* and Xin-Yuan Liu,* "Amide Groups Switch Selectivity: C–H Trifluoromethylation of α,β-Unsaturated Amides and Subsequent Asymmetric Transformation" Org. Lett., 2014, 16, 6032.

9. Jin-Shun Lin, Xiang-Geng Liu, Xiao-Long Zhu, Bin Tan,* and Xin-Yuan Liu,* “Copper-Catalyzed Aminotrifluoromethylation of Unactivated Alkenes with TMSCF3: Construction of Trifluoromethylated Azaheterocycles" J. Org. Chem. 2014, 79, 7084.

8. Xing-Li Zhu, Jin-Hui Xu, Dao-Juan Cheng, Li-Jiao Zhao, Xin-Yuan Liu,* and Bin Tan,* "In Situ Generation of Electrophilic Trifluoromethylthio Reagents for Enantioselective Trifluoromethylthiolation of Oxindoles" Org. Lett. 2014, 16, 2192.

7. Ya-Ping Xiong, Ming-Yue Wu, Xiang-Yu Zhang, Can-Liang Ma, Lin Huang, Li-Jiao Zhao, Bin Tan,* and Xin-Yuan Liu,* "Direct Access to α-CF3-enones via Efficient Copper-Catalyzed Trifluoromethylation of Meyer-Schuster Rearrangement" Org. Lett. 2014, 16, 1000.

6. Lei Li, Min Deng, Sheng-Cai Zheng, Ya-Ping Xiong, Bin Tan,* and Xin-Yuan Liu,* "Metal-Free Direct Intramolecular Carbotrifluoromethylation of Alkenes to Functionalized Trifluoromethyl Azaheterocycles." Org. Lett. 2014, 16, 504.

5. Jin-Shun Lin, Ya-Ping Xiong, Can-Liang Ma, Li-Jiao Zhao, Bin Tan,* and Xin-Yuan Liu,* "Efficient Copper-Catalyzed Direct Intramolecular Aminotrifluoromethylation of Unactivated Alkenes with Diverse Nitrogen-Based Nucleophiles." Chem. Eur. J. 2014, 20, 1332.

4. Tao Liu, Da-Qiang Li, Si-Yu Wang Yong-Zhou Hu, Xiao-Wu Dong,* Xin-Yuan Liu,* and Chi-Ming Che, "Straightforward Installation of Carbon-Halogen, Carbon-Oxygen and Carbon-Carbon Bonds within Metal–Organic Frameworks via Direct C–H Functionalization." Chem. Commun. 2014, 50, 13261.

3. Tao Liu, Jin-Xin Che, Yong-Zhou Hu, Xiao-Wu Dong,* Xin-Yuan Liu,* and Chi-Ming Che "Alkenyl/thiol-derived Metal–Organic Frameworks via Post-Synthetic Modification for Effective Mercury Adsorption." Chem. Eur. J. 2014, 20, 14090.

2. Xiao-Wu Dong, Tao Liu, Yong-Zhou Hu,* Xin-Yuan Liu,* and Chi-Ming Che "Urea Postmodified in Metal-Organic Framework as Catalytically Active Hydrogen-Bond-Donating Heterogeneous Catalyst." Chem. Commun. 2013, 49, 7681.

1. Gaosheng Yang,* Chongrong Luo, Xiaolong Mu, Tingting Wang, and Xin-Yuan Liu,* "Highly efficient enantioselective three-component synthesis of 2-amino-4H-chromenes catalysed by chiral tertiary amine-thioureas." Chem. Commun. 2012, 48, 5880.